Robert Rottapel Selected Research

Autoantibodies

1/2021	Anticardiolipin and other antiphospholipid antibodies in critically ill COVID-19 positive and negative patients.
3/2015	Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice.

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Robert Rottapel Research Topics

Disease

26	Neoplasms (Cancer) 09/2023 - 06/2002
10	Cherubism 01/2023 - 04/2007
8	Ovarian Neoplasms (Ovarian Cancer) 05/2024 - 02/2012
6	Inflammation (Inflammations) 09/2023 - 06/2010
4	Carcinogenesis 09/2023 - 03/2016
4	Breast Neoplasms (Breast Cancer) 01/2021 - 04/2014
3	Carcinoma (Carcinomatosis) 11/2020 - 11/2019
2	Ovarian Epithelial Carcinoma 01/2023 - 01/2022
2	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 08/2021
2	Neoplasm Metastasis (Metastasis) 01/2022 - 05/2020
2	Ascites 01/2021 - 11/2019
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 01/2017
2	Arthritis (Polyarthritis) 03/2015 - 01/2008
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 12/2023
1	Nephrotic Syndrome (Syndrome, Nephrotic) 12/2023
1	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 12/2023
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Cysts 01/2021
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2021
1	Critical Illness (Critically Ill) 01/2021
1	COVID-19 01/2021
1	Thrombosis (Thrombus) 01/2021
1	Respiratory Insufficiency (Respiratory Failure) 01/2021
1	Gout 12/2020
1	Periodontitis 01/2020
1	Alveolar Bone Loss 01/2020
1	Bone Resorption 01/2020
1	Chromosomal Instability (Chromosome Stability) 11/2019
1	Metabolic Bone Diseases (Osteopenia) 06/2017
1	Experimental Arthritis 03/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2014

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 12/2023 - 06/2002
6	TankyrasesIBA 01/2023 - 12/2011
5	Carrier Proteins (Binding Protein)IBA 01/2023 - 08/2011
5	Small Interfering RNA (siRNA)IBA 01/2022 - 02/2012
4	CytokinesIBA 09/2023 - 07/2010
4	Phosphotransferases (Kinase)IBA 05/2020 - 07/2003
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2014
3	DNA (Deoxyribonucleic Acid)IBA 04/2017 - 08/2005
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 05/2024 - 01/2023
2	Niacinamide (Nicotinamide)FDA LinkGeneric 05/2024 - 01/2023
2	Immune Checkpoint InhibitorsIBA 08/2021 - 08/2020
2	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 04/2017
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2017
2	AutoantibodiesIBA 01/2021 - 03/2015
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2021 - 01/2021
2	GuanineIBA 11/2019 - 01/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2015 - 12/2014
1	Immunosuppressive Agents (Immunosuppressants)IBA 12/2023
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 09/2023
1	Ligases (Synthetase)IBA 01/2023
1	N-methyladenosineIBA 01/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022
1	Itraconazole (Sporanox)FDA LinkGeneric 01/2022
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2022
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2022
1	Chloroquine (Aralen)FDA LinkGeneric 01/2022
1	Antimalarials (Antimalarial Agents)IBA 01/2022
1	6-methyladenineIBA 01/2022
1	Antiphospholipid AntibodiesIBA 01/2021
1	Immunoglobulin G (IgG)IBA 01/2021
1	Immunoglobulin M (IgM)IBA 01/2021
1	RelaxinIBA 01/2021
1	Colchicine FDA LinkGeneric 12/2020
1	Uric Acid (Urate)IBA 12/2020
1	Indicators and Reagents (Reagents)IBA 11/2020
1	Junctional Adhesion Molecule AIBA 11/2020
1	Fibronectins (Fibronectin)IBA 05/2020
1	6- (1H- indazol- 6- yl)- N- (4- morpholinophenyl)imidazo(1,2- a)pyrazin- 8- amineIBA 01/2020
1	Eph Family Receptors (Eph Receptors)IBA 01/2020
1	tyrosine receptor (receptor, tyrosine)IBA 01/2020
1	Alkylating AgentsIBA 11/2019
1	PlatinumIBA 11/2019
1	Platinum Compounds (Compounds, Platinum)IBA 11/2019
1	Bortezomib (Velcade)FDA Link 11/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2019
1	Mechanistic Target of Rapamycin Complex 1IBA 11/2019
1	Proteasome InhibitorsIBA 11/2019
1	tremelimumabIBA 04/2019
1	GTP Phosphohydrolases (GTPases)IBA 01/2018
1	Monomeric GTP-Binding ProteinsIBA 01/2018
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 01/2018
1	NucleotidesIBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 06/2017
1	OsteocalcinIBA 06/2017
1	Liposomes (Liposome)IBA 04/2017
1	Rho Guanine Nucleotide Exchange FactorsIBA 01/2017
1	TetraspaninsIBA 01/2017
1	MicroRNAs (MicroRNA)IBA 03/2016
1	AntigensIBA 03/2015
1	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 03/2015
1	Syk KinaseIBA 12/2014
1	Tartrate-Resistant Acid PhosphataseIBA 12/2014
1	Macrophage Colony-Stimulating FactorIBA 12/2014

Therapy/Procedure

5	Therapeutics 01/2023 - 04/2014
3	Drug Therapy (Chemotherapy) 01/2023 - 04/2014
3	Immunotherapy 08/2021 - 04/2019
1	Critical Care (Surgical Intensive Care) 01/2021
1	Ligation 01/2020